Solvent?induced enantioselectivity reversal in a chiral metal organic framework

Solvent-induced enantioselectivity reversal is a rarely reported phenomenon in porous homochiral materials. Similar behavior has been studied chiral high performance liquid chromatography, where minor modifications to the mobile phase can induce elution order of two enantiomers on stationary column. We report first instance solvent-induced metal organic framework. Further, we highlight complex frameworks toward racemic mixtures presence solvents through racemate-solvent and loading experiments as well enantiopure-solvent experiments. hypothesize that this interesting selectivity likely be observed other competitive adsorption, nonchiral selective processes involving solvent.